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Neurophysiologic mechanisms of freezing of gait: disentangling phenotypic heterogeneity with mobile EEG and wearable kinematic sensors

About

Brief Summary

This is a Basic science study investigating electrophysiological mechanisms of freezing of gait. Study involves EEG and accelerometer recordings during walking in a clinic setting. Patients are asked not to take morning medications on day of study. Study duration: 2-3 hours in one visit to UCLA.

Eligibility

Minimum Age
N/A
Maximum Age
N/A

Key inclusions: Diagnosis of idiopathic Parkinsons disease by movement disorders neurologist. Also recruiting age-matched healthy controls

Key Exclusions:

  • Dementia (defined as MOCA < 19)
  • Active hallucinations or psychosis
  • Contraindications to MRI (metal implant, claustrophobia).
  • History of Deep Brain Surgery (DBS)

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Protocol No.
21-000624
Category
Brain/Neurological Diseases
Healthy Volunteers
Contact
CrossLab Research