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An Organoid-based Functional Precision Medicine Trial in Osteosarcoma

About

Brief Summary

The purpose of this study is to examine if we can predict sensitivity of osteosarcoma to different chemotherapy agents using tissue cultures in the laboratory. We know that different chemotherapy agents can be used in the treatment, but not every sarcoma responds to them equally. It is important to understand if testing of the tissue obtained during a routine biopsy or surgery may be useful in selecting appropriate treatments. In addition, additional testing of the tumor, including genetic testing, will help us to understand osteosarcoma better.

Study Type
Observational
Phase
N/A

Eligibility

Gender
All
Healthy Volunteers
No
Minimum Age
N/A
Maximum Age
N/A

Inclusion / exclusion criteria - Group1:

  • Patients without diagnosis of osteosarcoma and whose imaging studies are suggestive of osteosarcoma and who are planned to undergo biopsy or surgery for diagnostic purposes

Inclusion / exclusion criteria - Group 2:

  • Patients whose imaging studies are suggestive of metastatic osteosarcoma and who are planned to undergo biopsy or surgery for diagnostic purposes

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Study Stats
Protocol No.
23-001212
Category
Sarcoma
Principal Investigator
ALICE SORAGNI
Contact
Bartosz Chmielowski
Location
  • UCLA Santa Monica
  • UCLA Westwood
For Providers
NCT No.
NCT06064682
For detailed technical eligibility, visit ClinicalTrials.gov.