Hanadi Ajam Oughli, MD

1. JRS McVoy, Hanadi Ajam Oughli, and Unsong Oh. Liver X Receptor- Dependent Inhibition of Microglial Nitric Oxide Synthase 2. Journal of Neuroinflammation 27th ser. 2015.12 (2015)
2. Karam M, Ajam Oughli H, Rabius R, Beneventi D, Wippold R, Blalock J.A, Cinciripini P.M Tobacco Cessation Treatment Pathways for Cancer Patients: 10 years in the making. Journal of National Comprehensive Cancer Network. July 2016.
3. Chen I, Fohtung R, Ajam Oughli H, Bauer R, Mattar C, Powderly W, Thoelke M. Concurrent Ramsay Hunt syndrome and disseminated herpes zoster in a patient with relapsed chronic lymphocytic leukemia. IDCases. Volume 6. 2016 (79-82).
4. Hanadi Ajam Oughli, Allison Chen, Philip Miller, Ginger Nicol, Meryl Butters, Michael Avidan, Susan Stark, Eric Lenze. Cognitive improvement in older adults in the year after hip fracture: implications for brain resilience in advanced aging. Am J Geriatr Psychiatry. 2018;26(11):1119-1127.
5. H. Oughli, H., E.J. Lenze, E.J., Locke, A.E., Yingling, M.D., Zhong, Y., Miller,J.P., Reynolds, C.F, Mulsant, B.H., Newcomer, J.W., Peterson, T.R., Müller, D.J., Nicol G.E. Getting to Precision Psychopharmacology: Combining Clinical and Genetic Information to Predict Fat Gain from Aripiprazole. Journal of Psychiatric Research, 2019 Jul; 114:67-74.
6. E. Lenze, H. Oughli. “Antidepressant Treatment for Late-Life Depression: Considering Risks and Benefits.” Journal of American Geriatric Society. 2019 Aug;67(8):1555-1556.
7. Buchalter ELF*, Oughli HA*, Lenze EJ, Dixon D, Miller JP, Blumberger D, Karp J, Reynolds CF, Mulsant BH. Predicting Remission in Late-Life Major Depression: A Clinical Algorithm Based upon Past Treatment History. Journal of Clinical Psychiatry.2019; 80(6). *Co-first authors.
8. Brooks H*, Ajam Oughli H*, Kamel L, Subramanian S, Morgan G, Blumberger D, Kloeckner J, Kumar S, Mulsant B, Lenze E, Rajji T. Enhancing Cognition in Older Persons with Depression or Anxiety with a Combination of Mindfulness-Based Stress Reduction (MBSR) and transcranial Direct Current Stimulation (tDCS): Results of a Pilot Randomized Clinical Trial. Mindfulness (2021). https://doi.org/10/1007/s12671-021-01764-9 . *Co-first authors.
9. Fox M, Siddarth P, Oughli HA, Nguyen SA, Milillo MM, Aguilar Y, Ercoli L, Lavretsky H. Women who breastfeed exhibit cognitive benefits after age 50. Evol Med Public Health. 2021 Oct 1;9(1):322-331. doi: 10.1093/emph/eoab027. PMID: 34754453; PMCID: PMC8573189.
10. ​​​​​​​Oughli H.A, Nguyen S.A., Siddarth P., Fox M., Milillo M., Ercoli L., Lavretsky H., The effect of cumulative lifetime estrogen exposure on cognition in depressed versus non-depressed older women. The Journal of Psychiatry and Neurology. 2022 Apr 11:8919887221090216. Doi:10.1177/08919887221090216. Epub ahead of print. PMID: 35410535.
11. ​​​​​​​Oughli HA, Gebara MA, Ciarleglio A, Lavretsky H, Brown PJ, Flint AJ, Farber NB, Karp JF, Mulsant BH, Reynolds CF 3rd, Roose SP, Yang L, Butters MA, Lenze EJ. Intravenous Ketamine for Late-Life Treatment-Resistant Depression: A Pilot Study of Tolerability, Safety, Clinical Benefits, and Effect on Cognition. Am J Geriatr Psychiatry. 2023 Mar;31(3):210-221. doi: 10.1016/j.jagp.2022.11.013. Epub 2022 Dec 5. PMID: 36529623.
12. ​​​​​​​Oughli HA, Simmons S, Nguyen SA, Lavretsky H. Resilience and mind-body interventions in late-life depression. Current Psychiatry. 2022;21(12):29.
13. Siddarth P, Abikenari M, Grzenda A, Cappelletti M, Oughli H, Liu C, Millillo MM, Lavretsky H. Inflammatory Markers of Geriatric Depression Response to Tai Chi or Health Education Adjunct Interventions. Am J Geriatr Psychiatry. 2023 Jan;31(1):22-32. doi: 10.1016/j.jagp.2022.08.004. Epub 2022 Aug 27. PMID: 36175271.
14. Lenze EJ, Mulsant BH, Roose SP, Lavretsky H, Reynolds CF 3rd, Blumberger DM, Brown PJ, Cristancho P, Flint AJ, Gebara MA, Gettinger TR, Lenard E, Miller JP, Nicol GE, Oughli HA, Pham VT, Rollman BL, Yang L, Karp JF. Antidepressant Augmentation versus Switch in Treatment-Resistant Geriatric Depression. N Engl J Med. 2023 Mar 23;388(12):1067-1079. doi: 10.1056/NEJMoa2204462. Epub 2023 Mar 3. PMID: 36867173.
15. Nguyen SA, Oughli HA, Lavretsky H. Novel strategies to promote well-being and positive aging. Int Psychogeriatr. 2023 Apr;35(4):165-166. doi: 10.1017/S1041610223000200. PMID: 36971197.
16. Vanderschelden B, Gebara MA, Oughli HA, Butters MA, Brown PJ, Farber NB, Flint AJ, Karp JF, Lavretsky H, Mulsant BH, Reynolds CF 3rd, Roose SP, Lenze EJ. Change in patient-centered outcomes of psychological well-being, sleep, and suicidality following treatment with intravenous ketamine for late-life treatment-resistant depression. Int J Geriatr Psychiatry. 2023 Jul;38(7):e5964. doi: 10.1002/gps.5964. PMID: 37392089.
17. Subramanian S, Oughli HA, Gebara MA, Palanca BJA, Lenze EJ. Treatment-Resistant Late-Life Depression: A Review of Clinical Features, Neuropsychology, Neurobiology, and Treatment. Psychiatr Clin North Am. 2023 Jun;46(2):371-389. doi: 10.1016/j.psc.2023.02.008. Epub 2023 Mar 27. PMID: 37149351.
18. Nguyen SA, Oughli HA, Lavretsky H. Complementary and Integrative Medicine for Neurocognitive Disorders and Caregiver Health. Curr Psychiatry Rep. 2022 Sep;24(9):469-480. doi: 10.1007/s11920-022-01355-y. Epub 2022 Aug 13. PMID: 35962927; PMCID: PMC9411083.
19. Oughli HA, Lee EE. Lonely for Life? Differences Between Chronic and Transient Loneliness and Their Impact on Depression in Older Adults. Am J Geriatr Psychiatry. 2023 Dec 22:S1064-7481(23)00515-8. doi: 10.1016/j.jagp.2023.12.012. Epub ahead of print. PMID: 38176966.
20. Leuchter MK, Citrenbaum C, Wilson AC, Tibbe TD, Jackson NJ, Krantz DE, Wilke SA, Corlier J, Strouse TB, Hoftman GD, Tadayonnejad T, Koek RJ, Slan AR, Ginder ND, Distler MG, Artin H, Lee JH, Adelekun AE, Einstein EH, Oughli HA, Leuchter AF. The effect of older age on outcomes of rTMS treatment for treatment-resistant depression. International Psychogeriatrics. Published online 2024:1-6. Doi:10.1017/S104161-224000462
21. Slan AR, Citrenbaum C, Corlier J, Ngo D, Vince-Cruz N, Jackson NJ, Valles TE, Wilke SA, Hoftman GD, Koek RJ, Leuchter MK, Krantz DE, Strouse TB, Tadayonnejad R, Ginder ND, Distler MG, Lee JH, Adelekun AE, Einstein EH, Oughli HA, Leuchter AF. The role of sex and age in the differential efficacy of 10 Hz and intermittent Theta-burst (iTBS) repetitive transcranial magnetic stimulation (rTMS) treatment of major depressive disorder (MDD). J Affect Disord. 2024 Aug 24:S0165-0327(24)01358-2. doi: 10.1016/j.jad.2024.08.129. Epub ahead of print. PMID: 39187197.

IV Ketamine for Resistant Depression in the Elderly: New Data

New Brain Aging Travel Fellowship for Neuroscience, 2022

NIMH Research Career Institute in Mental Health of Aging, 2020

Paula J. Clayton MD Hawthorne Foundation Research Award, 2018     

American Association of Geriatric Psychiatry Honors Scholarship, 2018 

Phi Beta Kappa Honor Society, 2008

Late-Life Treatment-Resistant Depression

Hanadi Ajam Oughli, MD

Polypharmacy in Older Adults