Soban Umar, MD, PhD

Link to complete list of published work >(Link is external) (Link opens in new window)

Recent Publications:

1. Partownavid P, Sharma S, Li J, Umar S, Rahman S, Eghbali M (2015). Involvement of Opioid Receptors in the Lipid Rescue of Bupivacaine-Induced Cardiotoxicity.(Link is external) (Link opens in new window) Anesth Analg. 2015 Aug;121(2):340-7. doi: 10.1213/ANE.0000000000000788. PMID: 25993392
2. Sharma S, Umar S, Centala A, Eghbali M (2015). Role of miR206 in genistein-induced rescue of pulmonary hypertension in monocrotaline model.(Link is external) (Link opens in new window) J Appl Physiol (1985). 2015 Dec 15;119(12):1374-82. doi: 10.1152/japplphysiol.00699.2014. Epub 2015 Oct 15. PMID: 26472874
3. Iorga A, Li J, Sharma S, Umar S, Bopassa JC, Nadadur RD, Centala A, Ren S, Saito T, Toro L, Wang Y, Stefani E, Eghbali M (2016). Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy.(Link is external) (Link opens in new window) J Am Heart Assoc. 2016 Jan 22;5(1). pii: e002482. doi: 10.1161/JAHA.115.002482. PMID: 26802104
4. Anwar A, Ruffenach G, Mahajan A, Eghbali M, Umar S (2016). Novel biomarkers for pulmonary arterial hypertension(Link is external) (Link opens in new window) (2016). Respir Res. (Impact Factor 3.841). 2016 Jul 20;17(1):88. doi: 10.1186/s12931-016-0396-6. Review. PubMed PMID: 27439993; PubMed Central PMCID: PMC4955255.
5. Sharma S, Ruffenach G, Umar S, Motayagheni N, Reddy ST, Eghbali M (2016). Role of oxidized lipids in pulmonary arterial hypertension(Link is external) (Link opens in new window) (2016). Pulm Circ. (Impact Factor 2.178). 2016 Sep;6(3):261-73. doi: 10.1086/687293. Review. PubMed PMID: 27683603; PubMed Central PMCID: PMC5019079.
6. Li J, Ruffenach G, Kararigas G, Cunningham CM, Motayagheni N, Barakai N, Umar S, Regitz-Zagrosek V, Eghbali M (2017). Intralipid protects the heart in late pregnancy against ischemia/reperfusion injury via Caveolin2/STAT3/GSK-3β pathway.(Link is external) (Link opens in new window) J Mol Cell Cardiol. (Impact Factor 5.680). 2017 Jan;102:108-116. doi: 10.1016/j.yjmcc.2016.11.006. PubMed PMID: 27847332.
7. Umar S, Partow-Navid R, Ruffenach G, Iorga A, Moazeni S, Eghbali M (2017). Severe Pulmonary Hypertension in Aging Female Apolipoprotein E Deficient Mice is Rescued by Estrogen Replacement Therapy.(Link is external) (Link opens in new window) Biol Sex Differ. (Impact Factor 3.635). 2017 Mar 20;8:9. doi: 10.1186/s13293-017-0129-7. eCollection 2017. PMID: 28344760
8. Umar S, Cunningham CM, Itoh Y, Moazeni S, Vaillancourt M, Sarji S, Centala A, Arnold AP, Eghbali M (2017). The Y Chromosome Plays a Protective Role in Experimental Hypoxic Pulmonary Hypertension.(Link is external) (Link opens in new window) Am J Respir Crit Care Med. 2017 Sep 21. doi: 10.1164/rccm.201707-1345LE. [Epub ahead of print] PubMed PMID: 28934553.
9. Iorga A, Cunningham CM, Moazeni S, Ruffenach G, Umar S, Eghbali M (2017). The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy.(Link is external) (Link opens in new window) Biol Sex Differ. 2017 Oct 24;8(1):33. doi: 10.1186/s13293-017-0152-8. Review. PubMed PMID: 29065927; PubMed Central PMCID: PMC5655818.
10. Vaillancourt M, Chia P, Sarji S, Nguyen J, Hoftman N, Ruffenach G, Eghbali M, Mahajan A, Umar S (2017). Autonomic nervous system involvement in pulmonary arterial hypertension.(Link is external) (Link opens in new window) Respiratory Research 2017 18:201.

December 04, 2017. Genes on Y chromosome protect against pulmonary hypertension, study suggests(Link is external) (Link opens in new window)
August 27, 2014. Protein in ‘good cholesterol’ may be a key to treating pulmonary hypertension(Link is external) (Link opens in new window)
July 02, 2012. UCLA study looks at why heart attacks cause so much more damage in late pregnancy(Link is external) (Link opens in new window)
September 15, 2011. Estrogen treatment may help reverse severe pulmonary hypertension(Link is external) (Link opens in new window)
August 05, 2011. UCLA study shows man-made fat may limit damage to heart attack victims (UCLA Newsroom)

• Junior Faculty Research Award Association of University Anesthesiologists (AUA) Meeting Washington DC, USA (2017)
• UCLA Cardiovascular Theme Innovation Award (2017)
• Best of Basic Science Award American Society of Anesthesiologists Conference Chicago, IL, USA (2016)
• Leonard F. Walts, MD Research Excellence Award, Department of Anesthesiology, UCLA (2013-16)
• The White Mountain Research Award, WARC Meeting Los Angeles, CA (2014)
• FAER Resident Scholar Award American Society of Anesthesiologists Annual Conference New Orleans, LA, USA (2014)
• Olive View UCLA Resident of the Year Award Annual Resident Graduation ceremony at UCLA, Los Angeles, CA (2014)
• UCLA Chancellor’s Award for Postdoctoral Research nomination Los Angeles, CA (2012)
• Young Investigator Abstract Awards American Thoracic Society Annual Conference Denver (2011), San Francisco (2012), Philadelphia (2013), and Denver (2015)
• Young Investigator Award American Heart Association (AHA) Annual Scientific Sessions Chicago (2010), and Los Angeles (2012)

• uclahealth.org/anes
• uclahealth.org/anes/research/basic-translational-research