Steven J. Jonas, MD, PhD
- Pediatric Hematology Oncology
About
Dr. Jonas is a UCLA physician-scientist specializing in Pediatric Hematology/Oncology. He received a bachelor's degree in materials science & engineering and a master's degree in biomedical engineering prior to starting his medical training to pursue his M.D. and his Ph.D. degrees at UCLA through its NIH-supported Medical Scientist Training Program. Dr. Jonas completed his pediatric residency and fellowship training in pediatric hematology/oncology at UCLA Mattel Children's Hospital where he was the first trainee in a specialized physician-scientist track established by the Department of Pediatrics at the UCLA David Geffen School of Medicine.
He leads a multidisciplinary research team that targets the development and application of new nanotechnologies and methods to support the childhood cancer and regenerative medicine research communities in accelerating the discovery and implementation of innovative gene therapy approaches and diagnostic strategies. His research is primarily focused on the design of nanotechnologies that enable rapid, safe, cost-effective, and efficient delivery of genes and genome-editing machinery to immune and stem cells for manufacturing new gene and cellular therapies.
In 2019, Dr. Jonas received the prestigious Director's Early Independence Award from the National Institutes of Health. He is a member of the California NanoSystems Institute, the UCLA Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research, and the Jonsson Comprehensive Cancer Center and is a Young Investigator awardee of the Alex's Lemonade Stand Foundation for Childhood Cancer Research, the Hyundai Hope on Wheels Foundation, and the Tower Cancer Research Foundation.
Languages
Education
Medical Board Certifications
Fellowship
Residency
Degrees
Recognitions
- Super Doctors® Southern California Rising Stars 2020, 2021, 2023, 2024
- NIH Director’s Early Independence Award, 2019
- Nancy Ann Mendiburu Outstanding Advance in Cancer Research Award, 2019
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Hospital Affiliations
Ronald Reagan UCLA Medical Center
UCLA Santa Monica Medical Center
UCLA Mattel Children's Hospital
Medical Services
Research
Publications
- Current Approaches to Applying CRISPR/Cas9 Gene Editing Tools for Engineering Cell Therapies: Gene Editing Cargo and Delivery Systems - September 26, 2022.
- Coupling Lipid Labeling and Click Chemistry Enables Isolation of Extracellular Vesicles for Noninvasive Detection of Oncogenic Gene Alterations - March 9, 2022.
- Acoustofluidic sonoporation for gene delivery to human hematopoietic stem and progenitor cells - May 19, 2020.
- Dual Supramolecular Nanoparticle Vectors Enable CRISPR/Cas9-Mediated Knockin of Retinoschisin 1 Gene—A Potential Nonviral Therapeutic Solution for X-Linked Juvenile Retinoschisis - April 16, 2020.
- Lipid Bicelle Micropatterning Using Chemical Lift-Off Lithography - February 24, 2020.
An Absence of Lamin B1 in Migrating Neurons Causes Nuclear Membrane Ruptures and Cell Death - December 3, 2019. - Supramolecular Nanosubstrate-Mediated Delivery System Enables CRISPR/Cas9 Knockin of Hemoglobin Beta Gene for Hemoglobinopathie - October 23, 2020.
- Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma-Derived Extracellular Vesicles for Downstream Functional Studies - Septemeber 13, 2020.
- Precision Medicine in Pediatric Neurooncology: A Review - December 4, 2017.
- Multiple-Patterning Nanosphere Lithography for Fabricating Periodic Three-Dimensional Hierarchical Nanostructures - September 28, 2017.
- Hydrophobic Surfaces for Enhanced Differentiation of Embryonic Stem Cell-Derived Embryoid Bodies - September 12, 2008.
Insurance
- Aetna
- Anthem Blue Cross
- Blue Shield of California
- Centivo
- Cigna
- First Health
- Health Net of California
- Interplan (part of HealthSmart)
- L.A. Care
- Medicare Advantage
- MultiPlan
- UFCM Health System
- Prime Health Services
- Private Healthcare Systems (PHCS)
- TRICARE
- UnitedHealthcare
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Recognitions
- Super Doctors® Southern California Rising Stars 2020, 2021, 2023, 2024
- NIH Director’s Early Independence Award, 2019
- Nancy Ann Mendiburu Outstanding Advance in Cancer Research Award, 2019
- Hyundai Hope on Wheels Scholar Award, 2019
- Tower Cancer Research Foundation Career Development Award, 2018
- UCLA Department of Chemistry & Biochemistry Postdoctoral Scholar Award, 2018
- Society for Pediatric Research/Pediatric Academic Societies Fellow’s Basic Science Award, 2018
- Hyundai Hope on Wheels Young Investigator Award, 2017
- Alex’s Lemonade Stand Young Investigator Award, 2017