Bartosz Chmielowski, MD, PhD

Bartosz Chmielowski, MD, PhD

Clinical Professor, Department of Medicine, Hematology/Oncology

Languages

English, Polish

Specialty

Hematology and Oncology

Institutional Affiliation

Ronald Reagan UCLA Medical Center
UCLA Medical Center, Santa Monica

Education

Fellowship

Hematology-Oncology, UCLA School of Medicine, 2005 - 2008

Internship

Internal Medicine, Medical College of Georgia Hospital, 2001 - 2002

Degree

MD, Akademia Medyczna W Wroclawiu, 1995

Residency

Internal Medicine, Medical College of Georgia Hospital, 2002 - 2005

Board Certifications

Medical Oncology, American Board of Internal Medicine, 2008
Hematology, American Board of Internal Medicine, 2008
Internal Medicine, American Board of Internal Medicine, 2004

Contact Information

Phone

(310) 794-4955 - Westwood
(310) 829-5471 - Santa Monica

Clinical Interests

Melanoma, Sarcoma

Scientific Interests

Dr. Bartosz Chmielowski's research concentrates mainly on the end-part of translational projects, when the laboratory research is already studied in the clinical setting. He is interested in phase 1, phase 2 and phase 3 clinical trials in patients with melanoma and sarcoma.

Highlighted Publications

Sosman JA, Kim KB, Schuchter L, Gonzalez R, Pavlick AC, Weber JS, McArthur GA, Hutson TE, Moschos SJ, Flaherty KT, Hersey P, Kefford R, Lawrence D, Puzanov I, Lewis KD, Amaravadi RK, Chmielowski B, Lawrence HJ, Shyr Y, Ye F, Li J, Nolop KB, Lee RJ, Joe AK, Ribas A. Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib. N Engl J Med. 2012 Feb 23;366(8):707-14.

Su F, Viros A, Milagre C, Trunzer K, Bollag G, Spleiss O, Reis-Filho JS, Kong X, Koya RC, Flaherty KT, Chapman PB, Kim MJ, Hayward R, Martin M, Yang H, Wang Q, Hilton H, Hang JS, Noe J, Lambros M, Geyer F, Dhomen N, Niculescu-Duvaz I, Zambon A, Niculescu-Duvaz D, Preece N, Robert L, Otte NJ, Mok S, Kee D, Ma Y, Zhang C, Habets G, Burton EA, Wong B, Nguyen H, Kockx M, Andries L, Lestini B, Nolop KB, Lee RJ, Joe AK, Troy JL, Gonzalez R, Hutson TE, Puzanov I, Chmielowski B, Springer CJ, McArthur GA, Sosman JA, Lo RS, Ribas A, Marais R. RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors. N Engl J Med. 2012 Jan 19;366(3):207-15.

Shi H, Moriceau G, Kong X, Koya RC, Nazarian R, Pupo GM, Bacchiocchi A, Dahlman KB, Chmielowski B, Sosman JA, Halaban R, Kefford RF, Long GV, Ribas A, Lo RS. Preexisting MEK1 exon 3 mutations in V600E/KBRAF melanomas do not confer resistance to BRAF inhibitors. Cancer Discov. 2012 May;2(5):414-24. Epub 2012 Apr 1

Carvajal RD, Antonescu CR, Wolchok JD, Chapman PB, Roman RA, Teitcher J, Panageas KS, Busam KJ, Chmielowski B, Lutzky J, Pavlick AC, Fusco A, Cane L, Takebe N, Vemula S, Bouvier N, Bastian BC, Schwartz GK. KIT as a therapeutic target in metastatic melanoma. JAMA. 2011 Jun 8;305(22):2327-34.

Atefi M, von Euw E, Attar N, Ng C, Chu C, Guo D, Nazarian R, Chmielowski B, Glaspy JA, Comin-Anduix B, Mischel PS, Lo RS, Ribas A. Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway. PLoS One. 2011 Dec 14;6(12):e28973.