Delphine Lee, MD, PhD, FAAD

Delphine J. Lee, MD, PhD, FAAD

Health Sciences Clinical Associate Professor, Department of Medicine, Dermatology
Chief and Program Director, Division of Dermatology, Department of Medicine, Harbor-UCLA Medical Center
Director, Dermatology Service Line, Department of Health Services, Los Angeles County
Director, Cancer Biology and Immunotherapeutics Institute, The Lundquist Research Institute at Harbor-UCLA Medical Center
Investigator, The Lundquist Research Institute at Harbor-UCLA Medical Center

Languages

English

Specialty

Dermatology

Institutional Affiliation

Harbor-UCLA Medical Center
Saint John's Health Center

Education

Internship

Transitional Internship, Scripps Mercy Hospital, 2001 - 2002

Degrees

MD, UC San Diego School of Medicine, 2001
PhD, UC San Diego School of Medicine, 1999

Residency

Dermatology, UCLA School of Medicine, 2002 - 2006

Board Certification

Dermatology, American Board of Dermatology, 2006

Contact Information

Clinical Interests

Autoimmune Skin Diseases, Alopecia Areata, Dermatomyositis, Lupus, Morphea, Pemphigoid, Pemphigus, Vitiligo/Pigmentation Disorder

Scientific Interests

Dr. Delphine Lee is a dermatologist and immunologist who uses molecular and bioinformatics approaches at the site of disease to uncover mechanisms regulating human immunity as they relate to cancer, infections and autoimmunity.

Highlighted Publications

Geroyska S, Mejia I, Chan AA, Navarrete M, Pandey V, Kharpatin S, Noguti J, Wang F, Srole D, Chou TF, Wohlschlegel J, Nemeth E, Damoiseaux R, Shackelford DB, Lee DJ, Díaz B. N-Myristoytransferase Inhibition Causes Mitochondrial Iron Overload and Parthanatos in TIM17A-Dependent Aggressive Lung Carcinoma. Cancer Res Commun. 2024 Jul 1;4(7):1815-1833. doi: 10.1158/2767-9764.CRC-23-0428. PubMed PMID: 38949950; PubMed Central PMCID: PMC11270646. 

Kremenovic M, Chan AA, Feng B, Bäriswyl L, Robatel S, Gruber T, Tang L, Lee DJ, Schenk M. BCG hydrogel promotes CTSS-mediated antigen processing and presentation, thereby suppressing metastasis and prolonging survival in melanoma. J Immunother Cancer. 2022 Jun;10(6). doi: 10.1136/jitc-2021-004133. PubMed PMID: 35732347; PubMed Central PMCID: PMC9226922. 

Chung AW, Kozielski AJ, Qian W, Zhou J, Anselme AC, Chan AA, Pan PY, Lee DJ, Chang JC. Tocilizumab overcomes chemotherapy resistance in mesenchymal stem-like breast cancer by negating autocrine IL-1A induction of IL-6. NPJ Breast Cancer. 2022 Mar 8;8(1):30. doi: 10.1038/s41523-021-00371-0. PubMed PMID: 35260569; PubMed Central PMCID: PMC8904846. 

Chung AW, Anand K, Anselme AC, Chan AA, Gupta N, Venta LA, Schwartz MR, Qian W, Xu Y, Zhang L, Kuhn J, Patel T, Rodriguez AA, Belcheva A, Darcourt J, Ensor J, Bernicker E, Pan PY, Chen SH, Lee DJ, Niravath PA, Chang JC. A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer. Sci Transl Med. 2021 Dec 15;13(624):eabj5070. doi: 10.1126/scitranslmed.abj5070. Epub 2021 Dec 15. PubMed PMID: 34910551. 

Chan AA, Bashir M, Rivas MN, Duvall K, Sieling PA, Pieber TR, Vaishampayan PA, Love SM, Lee DJ. Characterization of the microbiome of nipple aspirate fluid of breast cancer survivors. Sci Rep. 2016 Jun 21;6:28061. doi: 10.1038/srep28061.