Jingran Ji, MD

Jingran Ji, MD

Clinical Instructor, Department of Medicine, Division of Hematology/Oncology

Languages

English

Education

Fellowship

Hematology/Oncology, City of Hope National Medical Center, 2024

Degrees

MD, Northwestern Feinberg School of Medicine, Chicago, IL, 2018
BA, Northwestern University, Evanston, IL, 2013

Residency

Internal Medicine, UC Davis, 2021

Board Certifications

Medical Oncology, American Board of Internal Medicine, 2023
Internal Medicine, American Board of Internal Medicine, 2021

Contact Information

Scientific Interests

Dr. Ji's research goal is to develop clinically meaningful ways to improve functional outcomes among adults who experience the negative accelerated aging effects of cancer and its treatments. To achieve this goal, he is interested in first understanding the underlying biological mechanisms that drive the observed accelerated aging effects of chemotherapy. One such mechanism is cellular senescence, a process where normal cells undergo terminal growth arrest in response to repeated stressors such as DNA damage. Cellular senescence is a normal process of human aging that appears to be amplified by cancer treatment. Studies are ongoing to determine how to best measure senescence burden in the body, how senescence burden is related to functional outcomes, and how they can intervene to reduce senescence burden.

Highlighted Publications

Ji J, Bae M, Sun C, Wildes T, Freedman R, Magnuson A, O’Connor T, Moy B, Klepin H, Chapman A, Tew W, Dotan E, Fenton M, Kim H, Katheria V, Gross C, Cohen H, Muss H, Sedrak M. Falls Prechemotherapy and Toxicity-related Hospitalization During Adjuvant Chemotherapy for Breast Cancer in Older Women: Results from the Prospective Multicenter HOPE Trial. Cancer. March 2024; 130(6): 936-946. PMID: 37962093.

Ji J, Sun C, Cohen H, Muss H, Sedrak M. Toxicity Risk Score and Clinical Decline After Adjuvant Chemotherapy in Older Breast Cancer Survivors. Journal of the National Cancer Institute. May 2023; 115(5):578-585. PMID: 36762832.

Ji J, Sun C, Cohen H, Synold T, Muss H, Sedrak M. Inflammation and Clinical Decline after Adjuvant Chemotherapy in Older Adults with Breast Cancer: Results from the Hurria Older PatiEnts (HOPE) Prospective Study. Journal of Clinical Oncology. September 2022; JCO2201217. January 2023; 41(2):307-315. Epub Sep 2022. PMID: 36126235.

Ji J, Sandhu J, Wang C, Fakih M. Metastatic pattern is a prognostic factor in BRAFV600E mutant colorectal cancer. Cancer Treat Res Commun. April 2023; 35:100714. Epub 2023 Apr 28. PMID: 37126990.

Ji J, Aredo J, Piper-Vallilo A, Huppert L, Rotow J, Husain H, Stewart S, Cobb R, Wakelee H, Blakely C, Wong M, Gubens, M, Madani M, Digumarthy S, McCoach C, Piotrowska Z, Neal J, Riess J. Osimertinib in Non-Small Cell Lung Cancer (NSCLC) with Atypical EGFR Activating Mutations: A Retrospective Multicenter Study. Journal of Thoracic Oncology Clinical and Research Reports. January 2023; 4(3): 100459. PMID: 36879929.