Grants and Support
Anthony J. Aldave, MD
California Institute for Regenerative Medicine
Role: Principal Investigator
Duration: 08/01/23-02/28/26
Description: AAV gene therapy for treating congenital hereditary endothelial dystrophy associated with biallelic SLC4A11 mutations
Foundation for the National Institutes of Health
Accelerating Medicines Partnership® (AMP®) Bespoke Gene Therapy Consortium (BGTC)
Role: Principal Investigator
Duration: 05/28/23-05/27/28
Description: Phase I/II Safety and Efficacy Study of AAV-SLC4A11 Vector to Treat Congenital Hereditary Endothelial Dystrophy (CHED)
Santen Pharmaceuticals
Role: Site Principal Investigator
Duration: 02/02/23-02/01/25
Description: A Phase 2a, Randomized, Double-Masked, Placebo-Controlled, Parallel-Group, Multicenter Study Assessing the Efficacy and Safety of STN1010904 Ophthalmic Suspension 0.03% and 0.1% Compared with Vehicle in Subjects with Fuchs endothelial corneal dystrophy
Doug Chung, PhD
Eye Bank Association of America
Role: Principal Investigator
Duration: 07/01/23-06/30/24
Description: Characterizing the transcriptomic profiles of cultured ex vivo corneal endothelial cells treated with mitochondria-targeted antioxidants during cell expansion
Wenlin Zhang, MD, PhD
Foundation for the National Institutes of Health
Accelerating Medicines Partnership® (AMP®) Bespoke Gene Therapy Consortium (BGTC)
Role: Co-Principal Investigator
Duration: 05/28/23-05/27/28
Description: Phase I/II Safety and Efficacy Study of AAV-SLC4A11 Vector to Treat Congenital Hereditary Endothelial Dystrophy (CHED)
California Institute for Regenerative Medicine
Role: Co-Principal Investigator
Duration: 08/01/23-02/28/26
Description: AAV gene therapy for treating congenital hereditary endothelial dystrophy associated with biallelic SLC4A11 mutations