Endocrinology

Reviews & Editorials

REVIEWS

  1. Abel E D, Houseknecht K, Kahn B. Recent advances in understanding the molecular basis for insulin stimulated glucose transport, Diabetes. 1995;2(4):313-324. doi: 10.1097/00060793-199508000-00006.
  2. Abel E. Glucose transport in the heart, Frontiers in Bioscience. 2004;9:201-5. doi: 10.2741/1216.
  3. O'Neill BT, Abel ED. Akt1 in the cardiovascular system: friend or foe?, The Journal of clinical investigation. 2005 August 1;115(8):2059-64. PMID:16075047. doi: 10.1172/JCI25900.
  4. Abel E. Metabolic perturbations in the diabetic heart: mechanisms and molecular targets, Drug Discovery Today: Disease Mechanisms. 2005;2:115-122. doi: 10.1016/j.ddmec.2005.04.002.
  5. Abel E. Myocardial insulin resistance and cardiac complications of diabetes, Current Drug Targets, Immune, Endocrine & Metabolic Disorders. 2005;5(2):219-26. doi: 10.2174/1568008054064869.
  6. Boudina S, Abel E. Mitochondrial uncoupling: a key contributor to reduced cardiac efficiency in diabetes, Physiology. 2006;21:250-8. doi: 10.1152/physiol.00008.2006.
  7. Boudina S, Abel E. Diabetic cardiomyopathy revisited, Circulation. 2007;115(25):3213-23. doi: 10.1161/CIRCULATIONAHA.106.679597.
  8. Abel E. Glucose for the aging heart?, Circulation. 2007;116(8):884-887. doi: 10.1161/CIRCULATIONAHA.107.723015.
  9. Hsueh W, Abel E, Breslow J, Maeda N, Davis R, Fisher E, Dansky H, McClain D, McIndoe R, Wassef M, Rabadan-Diehl C, Goldberg I. Recipes for creating animal models of diabetic cardiovascular disease, Circulation Research. 2007;100(10):1415-27. doi: 10.1161/01.RES.0000266449.37396.1f.
  10. Abel E, Litwin S, Sweeney G. Cardiac remodeling in obesity, Physiological Reviews. 2008;88(2):389-419. doi: 10.1152/physrev.00017.2007.
  11. Bugger H, Abel E. Molecular basis of cardiac efficiency, Heart and Metabolism: Management of the Coronary Patient. 2008;39:5-9.
  12. Bugger H, Abel E. Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome, Clinical Science (London, England). 2008;114(3):195-210. doi: 10.1042/CS20070166.
  13. Bugger H, Abel E. Rodent models of diabetic cardiomyopathy, Disease Models and Mechanisms. 2009;2(9-10):454-66. doi: 10.1242/dmm.001941.
  14. Boudina S, Abel E. Diabetic cardiomyopathy, causes and effects, Reviews in Endocrine & Metabolic Disorders. 2010;11:31-9. doi: 10.1007/s11154-010-9131-7.
  15. Abel E. Free fatty acid oxidation in insulin resistance and obesity, Heart and Metabolism: Management of the Coronary Patient. 2010;48:1-6.
  16. Wende A, Abel E. Lipotoxicity in the heart, Biochimica et Biophysica Acta. 2010;1801(3):311-9. doi: 10.1016/j.bbalip.2009.09.023.
  17. Bugger H, Abel E. Mitochondria in the diabetic heart, Cardiovascular Research. 2010;88(2):229-40. doi: 10.1093/cvr/cvq239.
  18. Abel E, Doenst T. Mitochondrial adaptations to physiological versus pathological cardiac hypertrophy, Cardiovascular Research. 2011;90(2):234-42. doi: 10.1093/cvr/cvr015.
  19. Abel E, O'Shea K, Ramasamy R. Insulin resistance: metabolic mechanisms and consequences in the heart, Arteriosclerosis, Thrombosis, and Vascular Biology (online). 2012;32(9):2068-76. doi: 10.1161/ATVBAHA.111.241984.
  20. Abel E, Sweeney G. Modulation of the cardiovascular system by leptin, Biochimie. 2012;94:2097-103. doi: 10.1016/j.biochi.2012.03.019.
  21. Riehle C, Abel E. PGC-1 proteins and heart failure, Trends in Cardiovascular Medicine. 2012;22(4):98-105. doi: 10.1016/j.tcm.2012.07.003.
  22. Ardehali H, Sabbah H, Burke M, Sarma S, Liu P, Cleland J, Maggioni A, Gregg C, Fonarow G, Abel E, Campia U, Gheorghiade M. Targeting myoardial sustrate metabolism in heart failure: potential for new therapies, European Journal of Heart Failure. 2012;14:120-9. doi: 10.1093/eurjhf/hfr173.
  23. Symons JD, Abel ED. Lipotoxicity contributes to endothelial dysfunction: a focus on the contribution from ceramide., Reviews in endocrine & metabolic disorders. 2013 March 1;14(1):59-68. PMID:23292334. doi: 10.1007/s11154-012-9235-3.
  24. Doenst T, Nguyen T, Abel E. Cardiac Metabolism in Heart Failure-Implications Beyond ATP Production, Circulation Research. 2013;113:709-724. doi: 10.1161/CIRCRESAHA.113.300376.
  25. Riehle C, Abel ED. Insulin regulation of myocardial autophagy., Circulation journal : official journal of the Japanese Circulation Society. 2014 January 1;78(11):2569-76. PMID:25327953.
  26. Bugger H, Abel ED. Molecular mechanisms of diabetic cardiomyopathy., Diabetologia. 2014 April;57(4):660-71. PMID:24477973. PMCID: 3969857. doi: 10.1007/s00125-014-3171-6.
  27. Taegtmeyer H, Young ME, Lopaschuk GD, Abel ED, Brunengraber H, Darley-Usmar V, Des Rosiers C, Gerszten R, Glatz JF, Griffin JL, Gropler RJ, Holzhuetter HG, Kizer JR, Lewandowski ED, Malloy CR, Neubauer S, Peterson LR, Portman MA, Recchia FA, Van Eyk JE, Wang TJ. Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association., Circulation research. 2016 March 24. PMID:27012580. doi: 10.1161/RES.0000000000000097.
  28. Riehle C, Abel ED. Insulin Signaling and Heart Failure., Circulation research. 2016 April 1;118(7):1151-69. PMID:27034277. doi: 10.1161/CIRCRESAHA.116.306206.
  29. Jaishy B, Abel ED. Lipids, Lysosomes and Autophagy., Journal of lipid research. 2016 June 21. PMID:27330054. doi: 10.1194/jlr.R067520.
  30. Kenny HC, Abel ED. Heart Failure in Type 2 Diabetes Mellitus., Circulation research. 2019 January 4;124(1):121-141. PMID:30605420. doi: 10.1161/CIRCRESAHA.118.311371.
  31. Ritchie RH, Abel ED. Basic Mechanisms of Diabetic Heart Disease., Circulation research. 2020 May 22;126(11):1501-1525. PMID:32437308. PMCID: PMC7251974. doi: 10.1161/CIRCRESAHA.120.315913.
  32. Abel ED. It takes a village: lessons from collaborative science., The Journal of clinical investigation. 2021 January 19;131(2). PMID:33463544. PMCID: PMC7810490. doi: 10.1172/JCI145962.
  33. Abel ED. mTOR Mediated Metabolic Rewiring and Ischemic Preconditioning, its Complicated., Circulation research. 2021 March 5;128(5):652-654. PMID:34219792. PMCID: PMC8244748. doi: 10.1161/circresaha.121.318874.
  34. Finn PW, Abel ED, Amin A, Anderson ME, Carethers JM, Coleman DL, Curtis AB, Geraci MW, Gladwin MT, Hollenberg A, Parmacek MS, Robbins RJ. Voices for Social Justice and Against Racism: An AAIM Perspective., The American journal of medicine. 2021 April 10. PMID:33848502. doi: 10.1016/j.amjmed.2021.03.008.
  35. Carter CS, Huang S, Searby C, Cassaidy B, Miller M, Grzesik W, Piorczynski TB, Pak TK, Walsh S, Acevedo M, Zhang Q, Mapuskar K, Milne G, Hinton, Jr AO, Guo DF, Weiss RM, Bradberry K, Taylor EB, Rauckhorst A, Dick D, Akurathi V, Falls-Hubert K, Wagner B, Carter W, Wang K, Norris AW, Rahmouni K, Buettner GR, Hansen JM, Spitz DR, Abel ED, Sheffield VC. Counterpoint regarding an alternative hypothesis for why exposure to static magnetic and electric fields treat type 2 diabetes., American journal of physiology. Endocrinology and metabolism. 2021 April 12. PMID:33843282. doi: 10.1152/ajpendo.00110.2021.
  36. Byrne NJ, Rajasekaran NS, Abel ED, Bugger H. Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy., Free radical biology & medicine. 2021 April 25;169:317-342. PMID:33910093. doi: 10.1016/j.freeradbiomed.2021.03.046.
  37. Carter CS, Huang SC, Searby CC, Cassaidy B, Miller MJ, Grzesik WJ, Piorczynski TB, Pak TK, Walsh SA, Acevedo M, Zhang Q, Mapuskar KA, Milne GL, Hinton, Jr AO, Guo DF, Weiss R, Bradberry K, Taylor EB, Rauckhorst AJ, Dick DW, Akurathi V, Falls-Hubert KC, Wagner BA, Carter WA, Wang K, Norris AW, Rahmouni K, Buettner GR, Hansen JM, Spitz DR, Abel ED, Sheffield VC. Reply to Petersen et al.: An alternative hypothesis for why exposure to static magnetic and electric fields treats type 2 diabetes., American journal of physiology. Endocrinology and metabolism. 2021 May 1;320(5):E1004-E1005. PMID:33843283. PMCID: PMC8238129. doi: 10.1152/ajpendo.00119.2021.
  38. Lopaschuk GD, Karwi QG, Tian R, Wende AR, Abel ED. Cardiac Energy Metabolism in Heart Failure., Circulation research. 2021 May 14;128(10):1487-1513. PMID:33983836. PMCID: PMC8136750. doi: 10.1161/CIRCRESAHA.121.318241.
  39. Abel ED. Insulin Signaling In the Heart., American journal of physiology. Endocrinology and metabolism. 2021 May 31. PMID:34056923. doi: 10.1152/ajpendo.00158.2021.
  40. Bugger H, Byrne NJ, Abel ED. Animal Models of Dysregulated Cardiac Metabolism. Circulation Research. 2022 130:1965-1993. doi: 10.1161/CIRCRESAHA.122.320334. PMC Pending.
  41. Felker GM, Buttrick P, Rosenzweig A, Abel ED, Allen LA, Bristow M, Das S, DeVore AD, Drakos SG, Fang JC, Freedman JE, Hernandez AF, Li DY, McKinsey TA, Newton-Cheh C, Rogers JG, Shah RV, Shah SH, Stehlik J, Selzman CH. Heart Failure Strategically Focused Research Network: Summary of Results and Future Directions. J Am Heart Assoc. 2022 11(18):e025517. doi: 10.1161/JAHA.122.025517. Epub 2022 Sep 8. PMC Pending.
  42. Deng, B., Zhang, Y., Zhu, C., Wang, Y., Weatherford, E., Xu, B., Liu, X., Conway, S. J., Abel, E. D., & Xiang, Y. K. (2023). Divergent Actions of Myofibroblast and Myocyte β2-Adrenoceptor in Heart Failure and Fibrotic Remodeling. Circulation research, 132(1), 106–108. https://doi.org/10.1161/CIRCRESAHA.122.321816

EDITORIALS

  1. Doenst T, Abel ED. Spotlight on metabolic remodelling in heart failure., Cardiovascular research. 2011 May 1;90(2):191-3. PMID:21429943. doi: 10.1093/cvr/cvr077.
  2. Abel E. A new twist in the function of the cardiac lipid droplet, Nature Medicine. 2011;17(9):1045-9. doi: 10.1038/nm.2432.
  3. Abel E. Obesity stresses cardiac mitochondria even when you are young, J Am Coll Cardiol. 2011;57(5):586-9. doi: 10.1016/j.jacc.2010.09.039.
  4. Bugger H, Abel E. Endonuclease G: the link between mitochondria and cardiac hypertrophy?, Circulation Research. 2012;110:378-80. doi: 10.1161/RES.0b013e318249dcc8.
  5. Nair KS, Abel ED, Adler SG, Dyck PJ, Gardner TW, Haskins KM, Hotamisligil G, Jensen MD, Krook A, Mandarino LJ, Mitchell BD, Pessin JE, Sowers JR, Sussel L, Wareham N, Vella A. Time to look back and to look forward., Diabetes. 2014 April 1;63(4):1169-70. PMID:24651796. doi: 10.2337/db14-0067.