Selected Recent Publications:

Crowell PD, Giafaglione JM, Hashimoto T, Diaz JA, Goldstein AS. Evaluating the Differentiation Capacity of Mouse Prostate Epithelial Cells Using Organoid Culture. J VisExp (2019) Nov 22;(153).
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Fox JJ, Navarro HI, Hashimoto T, Garcia AJ, Goldstein AS. Mass cytometry reveals species-specific differences and a new level of complexity for immune cells in the prostate. Am J Clin Exp Urol(2019), 7:281-296.
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Crowell PD, Fox JJ, Hashimoto T, Diaz JA, Navarro HI, Henry GH, Feldmar BA, Lowe MG, Garcia AJ, Wu YE, Sajed DP, Strand DW, Goldstein AS. Expansion of luminal progenitor cells in the aging mouse and human prostate. Cell Reports(2019), 28:1499-1510.
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Mottahedeh J, Haffner MC, Grogan TR, Hashimoto T, Crowell PD, Beltran H, Sboner A, Bareja R, Esopi D, Isaacs WB, Yegnasubramanian S, Rettig MB, Elashoff DA, Platz EA, De Marzo AM, Teitell MA, Goldstein AS. CD38 is methylated in prostate cancer and regulates extracellular NAD+. Cancer & Metabolism(2018), 6:13.
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Liu X, Grogan T, Hieronymus H, Hashimoto T, Mottahedeh J, Cheng D, Zhang L, Huang K, Stoyanova T, Park JW, Shkhyan RO, Nowroozizadeh B, Rettig MB, Sawyers CL, Elashoff D, Horvath S, Huang J, Witte ON, Goldstein AS. Low CD38 identifies progenitor-like inflammation-associated luminal cells that can initiate human prostate cancer and predict poor outcome. Cell Reports(2016), 17:2596-2606.
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Remacle F, Goldstein AS, Levine RD. Multivariate Surprisal Analysis of Gene Expression Levels. Entropy(2016), 18: 445; doi:10.3390/e18120445. 

Stoyanova T, Cooper AR, Drake JM, Liu X, Armstrong AJ, Pienta KJ, Zhang H, Kohn DB, Huang J, Witte ON, Goldstein AS. Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells. PNAS USA(2013), 110:20111-20116.
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Stoyanova T, Goldstein AS, Cai H, Drake JM, Huang J, Witte ON. Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via beta-catenin signaling. Genes & Development(2012), 26:2271-2285.
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Kravcheko-Balashaa N, Levitzki A, Goldstein A, Rotterd V, Grossb A, Remacle F, Levine RD. On a fundamental structure of gene networks in living cells. PNAS USA(2012), 109:4702-4707.
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Goldstein AS, Drake JM, Burnes DL, Finley DS, Zhang H, Reiter RE, Huang J, Witte ON. Purification and direct transformation of epithelial progenitor cells from primary human prostate. Nature Protocols(2011), 6:656-667.
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Goldstein AS, Huang J, Guo C, Garraway IP, Witte ON. Identification of a cell-of-origin for human prostate cancer. Science(2010), 329:568-571.
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