Research Updates
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Latest Research
UCLA Endocrine Surgery is committed to ongoing research in a quest to develop new treatments and cures for all for patients with conditions of the thyroid, parathyroid, and adrenal glands.
End-organ Effects of Primary Hyperparathyroidism: A population-based Study
![Surgery for Primary Hyperparathyroidism: Adherence to Consensus Guidelines in an Academic Health System](/sites/default/files/styles/max_width_004000_160/public/images/Consensus-PHPT-Surgery_8b1.jpg?itok=9kbpSck6)
Background: Patients with primary hyperparathyroidism are at risk for skeletal and renal end-organ damage. Methods: We studied patients with biochemically confirmed primary hyperparathyroidism from 1995–2014 and quantified the frequency of osteoporosis, nephrolithiasis, hypercalciuria, and decrease in renal function.
Link to Manuscript >
Gene Expression Classifier vs Targeted Next-Generation Sequencing in the Management of Indeterminate Thyroid Nodules
![Gene Expression Classifier vs Targeted Next-Generation Sequencing](/sites/default/files/styles/max_width_004000_160/public/images/Molecular-Markers-JCEM1.jpg?itok=ARCy3frH)
Objective: Compare the diagnostic performance of Afirma Gene Expression Classifier (GEC) with that of ThyroSeq v2 next-generation sequencing assay.
Link to Manuscript >
Surgery for Primary Hyperparathyroidism: Adherence to Consensus Guidelines in an Academic Health System
![Surgery for Primary Hyperparathyroidism: Adherence to Consensus Guidelines in an Academic Health System](/sites/default/files/styles/max_width_004000_160/public/images/Consensus-PHPT-Surgery_8b1.jpg?itok=9kbpSck6)
Objective: To determine the extent to which consensus guidelines for surgery in patients with primary hyperparathyroidism (PHPT) are followed within an academic health system.
Link to Manuscript >
![Factors Associated With Discordance Between Preoperative Parathyroid](/sites/default/files/styles/max_width_004000_160/public/images/Discordant_parathyroid_CT_1.jpg?itok=fmr2y50V)
Question: What factors contribute to discordance between preoperative parathyroid 4-dimensional computed tomographic scans and intraoperative findings?
Link to Manuscript >
![Sustained Growth of a University-Based Endocrine Surgery Program](/sites/default/files/styles/max_width_004000_160/public/images/Growth-of-academic1.jpg?itok=XPfZsEun)
Background: Endocrine surgery continues to mature as a subspecialty field. We describe the clinical performance of an academic endocrine surgery program (ESP) over its first 10 years.
Link to Manuscript >
![The Relationship of Parathyroidectomy and Bisphosphonates With Fracture Risk in Primary Hyperparathyroidism](/sites/default/files/styles/max_width_004000_160/public/images/Parathyroidectomy-fracture1.jpg?itok=vdWj0yOv)
Objective: To measure the relationship of parathyroidectomy and bisphosphonates with skeletal outcomes in patients with PHPT.
Link to Manuscript >
![Decreasing use of radioactive iodine for low risk thyroid cancer in California](/sites/default/files/styles/max_width_004000_160/public/images/RAI-ablation1.jpg?itok=FxdiYvfY)
Context: Routine radioactive iodine (RAI) ablation for low-risk differentiated thyroid cancer (DTC) is not supported by current practice guidelines. Objective: To assess recent stage-specific trends in utilization of RAI ablation.
Link to Manuscript >
![Single-incision retroperitoneoscopic adrenalectomy](/sites/default/files/styles/max_width_004000_160/public/images/Single_incision_adrenalectomy1.jpg?itok=hmXq4IWd)
Background: Endoscopic adrenalectomy is currently performed using multiple ports placed either transabdominally or retroperitoneally. We report our initial experience with single-incision retroperitoneoscopic adrenalectomy (SIRA).
Link to Manuscript >
![Risk Factors Associated With Reoperation and Disease-Specific Mortality in Patients With Medullary Thyroid Carcinoma](/sites/default/files/styles/max_width_004000_160/public/images/Thyroid-Carcinoma1.jpg?itok=BTuCBfzw)
Question: What is the association of initial neck dissection with the need for reoperation in medullary thyroid carcinoma?
Link to Manuscript >
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