Jesse Zamudio, PhD
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Scientific Interests
Dr. Jesse Zamudio's research interests include machanisms of RNA-mediated gene regulation in development and cancer.
Highlighted Publications
Bosson AD, Zamudio JR, Sharp PA. Endogenous miRNA and target concentrations determine susceptibility to potential ceRNA competition. Mol Cell. 2014 Nov 6;56(3):347-59. doi: 10.1016/j.molcel.2014.09.018. Epub 2014 Oct 23.
Dimitrova N, Zamudio JR, Jong RM, Soukup D, Resnick R, Sarma K, Ward AJ, Raj A, Lee JT, Sharp PA, Jacks T. LincRNA-p21 activates p21 in cis to promote Polycomb target gene expression and to enforce the G1/S checkpoint. Mol Cell. 2014 Jun 5;54(5):777-90. doi: 10.1016/j.molcel.2014.04.025. Epub 2014 May 22.
Zamudio JR, Kelly TJ, Sharp PA. Argonaute-bound small RNAs from promoter-proximal RNA polymerase II. Cell. 2014 Feb 27;156(5):920-34. doi: 10.1016/j.cell.2014.01.041.
Flynn RA, Almada AE, Zamudio JR, Sharp PA. Antisense RNA polymerase II divergent transcripts are P-TEFb dependent and substrates for the RNA exosome. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10460-5. doi: 10.1073/pnas.1106630108. Epub 2011 Jun 13.