Cytogenetics Laboratory

Contact Information

UCLA Pathology Outreach Client Services
Phone: 310-267-2680 | Email
Fax: 310-267-2685

New client account activation
Requisitions and supplies
Specimen requirements and transport
Report status and results
Arrange consult with pathologist assigned to case
Billing inquiries and assistance

Specimen delivery address:
UCLA Pathology Outreach
Specimen Receiving
10833 Le Conte Ave, A3-240 CHS
Los Angeles, CA 90095
Hours: Monday-Friday 6:00am-8:00pm

The UCLA Cytogenetics Laboratory is headed by ABMGG-certified Cytogeneticists and staffed by California-licensed Clinical Cytogenetics Scientists (CCS) and Hospital Laboratory Technicians (HLT). Our lab performs more than 8,000 cytogenetic assays annually for our in-patient population, community-based physicians and independently run pathology laboratories. This includes a high volume of hematological cases. State-of the art technologies are employed, including molecular cytogenetic techniques, such as fluorescence in situ hybridization (FISH) and chromosomal microarray analysis (CMA) for a wide range of clinical settings from cancer to prenatal and postnatal diagnosis.

Services

Oncology-Detection of cytogenetic molecular abnormalities in leukemias, lymphomas and solid tumors by standard and molecular cytogenetics, and molecular pathology.
Constitutional Prenatal and Postnatal-Diagnosis of microdeletion syndromes and numerical aberrations.

Forms

Oncology

Routine G-band chromosome analysis
Comprehensive FISH panels
SNP-Chromosomal Microarray Analysis (CMA)

Hematologic Malignancies

Acute Lymphocytic Leukemia (T-B ALL)
Acute Myelogenous Leukemia (AML)
Myelodysplastic Syndrome (MDS)
Myeloproliferative Neoplasms (MPN)
Chronic Myelogenous Leukemia (CML)
Non-Hodgkin's Lymphoma (NHL)
Plasma Cell Myeloma
Chronic Lymphocytic Leukemia (CLL)
Lymphoproliferative Disorder (LPD)

Solid Tumor

Uveal melanoma
Brain, CNS(Glioma, Neuroblastoma, Schwannoma/Rhabdoid)
Bladder
Breast
Soft tissue sarcoma (Ewing, alveolar rhabdomyosarcoma, myxoid/round cell liposarcoma, malignant liposarcoma/angiomatoid fibrous histiocytoma, well-differentiated liposarcoma)

Constitutional

Prenatal

Rapid fluorescence in situ hybridization (FISH) for aneuploidy screening.
- Interphase analysis for trisomies of 13, 18 and 21, and aneuploidies of chromosomes X and Y, provides rapid detection of the most common chromosomal aneuploidies
Routine G-band chromosome analysis
- Performed to obtain an overview of the fetal karyotype and chromosome structure in amniocytes, chorionic villi sampling and products of conception
SNP-Chromosomal Microarray Analysis (CMA) offers full genome coverage with nearly 2 million oligonucleotide markers

Postnatal

SNP-Chromosomal Microarray Analysis (CMA) offers full genome coverage with nearly 2 million oligonucleotide markers
Routine G-band chromosome analysis for couples with infertility or recurrent pregnancy loss

Faculty