Cytogenetics Laboratory
Contact Information
UCLA Pathology Outreach Client Services
Phone: 310-267-2680 | Email
Fax: 310-267-2685
- New client account activation
- Requisitions and supplies
- Specimen requirements and transport
- Report status and results
- Arrange consult with pathologist assigned to case
- Billing inquiries and assistance
Specimen delivery address:
UCLA Pathology Outreach
Specimen Receiving
10833 Le Conte Ave, A3-240 CHS
Los Angeles, CA 90095
Hours: Monday-Friday 6:00am-8:00pm
The UCLA Cytogenetics Laboratory is headed by ABMGG-certified Cytogeneticists and staffed by California-licensed Clinical Cytogenetics Scientists (CCS) and Hospital Laboratory Technicians (HLT). Our lab performs more than 8,000 cytogenetic assays annually for our in-patient population, community-based physicians and independently run pathology laboratories. This includes a high volume of hematological cases. State-of the art technologies are employed, including molecular cytogenetic techniques, such as fluorescence in situ hybridization (FISH) and chromosomal microarray analysis (CMA) for a wide range of clinical settings from cancer to prenatal and postnatal diagnosis.
- Oncology-Detection of cytogenetic molecular abnormalities in leukemias, lymphomas and solid tumors by standard and molecular cytogenetics, and molecular pathology.
- Constitutional Prenatal and Postnatal-Diagnosis of microdeletion syndromes and numerical aberrations.
Forms
Oncology
- Routine G-band chromosome analysis
- Comprehensive FISH panels
- SNP-Chromosomal Microarray Analysis (CMA)
Hematologic Malignancies
- Acute Lymphocytic Leukemia (T-B ALL)
- Acute Myelogenous Leukemia (AML)
- Myelodysplastic Syndrome (MDS)
- Myeloproliferative Neoplasms (MPN)
- Chronic Myelogenous Leukemia (CML)
- Non-Hodgkin's Lymphoma (NHL)
- Plasma Cell Myeloma
- Chronic Lymphocytic Leukemia (CLL)
- Lymphoproliferative Disorder (LPD)
Solid Tumor
- Uveal melanoma
- Brain, CNS(Glioma, Neuroblastoma, Schwannoma/Rhabdoid)
- Bladder
- Breast
- Soft tissue sarcoma (Ewing, alveolar rhabdomyosarcoma, myxoid/round cell liposarcoma, malignant liposarcoma/angiomatoid fibrous histiocytoma, well-differentiated liposarcoma)
Constitutional
Prenatal
- Rapid fluorescence in situ hybridization (FISH) for aneuploidy screening.
- Interphase analysis for trisomies of 13, 18 and 21, and aneuploidies of chromosomes X and Y, provides rapid detection of the most common chromosomal aneuploidies
- Routine G-band chromosome analysis
- Performed to obtain an overview of the fetal karyotype and chromosome structure in amniocytes, chorionic villi sampling and products of conception
- SNP-Chromosomal Microarray Analysis (CMA) offers full genome coverage with nearly 2 million oligonucleotide markers
Postnatal
- SNP-Chromosomal Microarray Analysis (CMA) offers full genome coverage with nearly 2 million oligonucleotide markers
- Routine G-band chromosome analysis for couples with infertility or recurrent pregnancy loss
Faculty
Sung-Hae Kang, PhD, FACMG
Clinical Director, Cytogenetics Laboratory
Associate Director, Molecular Diagnostics Laboratories
Wayne W. Grody, MD, PhD
Founding Director, Molecular Diagnostics Laboratories and Clinical Genomics
Alden Huang, PhD
Nagesh Rao, PhD, FACMG
Consultant, Cytogenetics Laboratory
T. Niroshi Senaratne, PhD
Associate Director, Cytogenetics Laboratory
Associate Director, Molecular Diagnostics Laboratories