Our Research

Research and education are integral components of our Center and are continuously pursued in an effort to provide all technological advances to our patients. The Kameron Gait and Motion Analysis Laboratory is used to aid in clinical decision-making and in the pursuit of research questions. Our basic research programs help us to understand the causes of movement disorders as well as assess the effectiveness of treatment. Educational programs target both professionals and patients.

Research Projects at the Center for cerebral palsy

Hip Surveillance in Cerebral Palsy

At the UCLA/OIC Center for Cerebral Palsy, we carefully surveil all children with CP for hips at risk of dislocating and treat with orthopaedic surgery, when appropriate. However, we have not studied our surveillance protocol scientifically. This study records our hip surveillance efforts and any surgical intervention performed so that we may improve our protocol here at UCLA and perfect the North American protocol that has been proposed by members of the Pediatric Orthopaedic Society of North America.
All children seen at the CCP are asked to participate, but if you would like further information, please contact us at [email protected]

Muscular Changes in Cerebral Palsy

CP is a disorder of movement that results from an injury to the developing brain.  While the brain injuries have been studied extensively previously, the resulting effects on the muscle are not well understood but include weakness and stiffness. No previous researcher has extensively evaluated the changes in that occurs as children with CP grow. To that point, we are currently studying small muscle biopsies from children with and without CP to better understand the changes that occur in CP muscle as a first step toward a better understanding of the disease, which will hopefully lead to future improvements in the care of patients with CP and other neuromuscular diseases.
If you would like to be included for study, and you or your child are planning on surgery at UCLA, please contact us at [email protected]

Peri-operative Use of a Pain Injection in Pediatric Patients with Cerebral Palsy

The purpose of this study is to evaluate the effectiveness of an injection of local pain medication in children with cerebral palsy undergoing major hip surgery. If your child is scheduled to undergo surgery and you choose to participate in this study, in addition to typical pain control, your child will also receive an injection directly into the surgical site. As this is a randomized control study, your child will receive either an injection of pain medication or a placebo.  Pain levels after surgery will be compared between the two groups to determine if this type of pain control is helpful in reducing post-operative pain in children with cerebral palsy. This study is not currently enrolling new patients.

Pre-Operative Video Counseling for Cerebral Palsy Patients

This study aims to establish an education program for CP patients and parents of CP patients undergoing orthopedic surgery. If you choose to participate, depending on which group you are assigned to, you and your child will receive either standard preoperative counseling alone or with the addition of a preoperative education program consisting of a short video and informative handouts. The education program will add approximately 20-30 minutes of time to your preoperative clinic visit. This study is not currently enrolling new patients.

Serum Markers in Pediatric CP

Cerebral palsy can cause muscle stiffness and weakness. There is some evidence that this stiffness and contractures result from increased inflammation – the body’s response to irritation and/or injury. The overall level of inflammation can be measured by markers of inflammation that circulate in the liquid portion of the blood – the “serum.” If your child is scheduled to undergo surgery and you choose to participate in this study, a small amount of your child’s blood will be drawn before and after surgery. The serum will be evaluated for inflammation so that we can better understand the nature of CP, which will hopefully lead to future improvements in the care.